为满足集团公司优质客户的广泛生物材料使用需求，公司长期以来提供国际小众品牌的代采购增值服务。经过多年的经验积累和客户反馈，已经建立了成熟完善的国际采购业务平台，美东美西两大合作集货点，自有快速审批和进出口通道。现将此服务开放给广大经销商合作伙伴和全国科研工作者，致力于缩短中国与国际一线研发的差距。
至今合作品牌多达300个以上，以下为部分合作品牌摘选
A: AB Biosciences 、ABP Biosciences、aldevron、Almac、Altogen Biosystems americanBIO、Amsbio、ANP Technologies、Antibody Solutions、Arrayit、ARENA CHEMICAL、A.COSTANTINO
B：Bel-Art、BGSC、Brooklyn Tool 、Biomatrica、Biopredic、BioControl、BioGenes
C：C Technologies、Central Drug House(P) Ltd、ChemScence、CHEMTRADE、CompTech、Coriell Institute、Creative Biolabs、Computype、Craic
D：D&M continuous、DiAgam、Diamond Materials、DocuSign、Dravon、Desert King
E：EdgeBio、EMC microcollections、ENVAIR、EXCEL Scientific、EMC microcollections
F：Faucet Queen、FinaBio
G：G&P Biosciences、Globe、GLO GERM、glycosynth
H：hellobio、HENKE-SASS WOLF、Higgins Analytical、HJ-BIOANALYTIK
I：Ivy Fine Chemicals、Invitek、Inycom Biotech、iQBIOSCIENCES
J：JCRB Cell Bank、
K：Kerafast、KOAMTAC
L：LAB BIO、LC Labs、LigaTrap、Lighthouse data、LP ITALIANA、Lumafluor、LYTIC SOLUTIONS
M：Medkoo、Maddak、MIMETAS、MiTeGen
N：Neuro Prob、NextGene、nippongenetics、NORTHWEST ANALYTICS、NovaBioAssays、NU-CHEK PREP
O：Orbital Biosciences 、OXITENO
P：PAR、PyMOL、Pharmaffiliates、Panagene、Pel Freez、PFEnex、Polylc、Proliant Biologicals
R：Riken、RANKIN、Ratiolab
S：SRL、SPD Scientific、Sanquin、Sbio、Scarab Genomics、Simport、SOVICELL、Starna cells
T：TSC、Tower optical corporation、TwistDx、TEKnova、Transposagen、Tribioscience、TriLink
U：Ultivue
X：ximbio
Z：Zymesci
特殊类别
细胞：Riken、JCRB Cell Bank、Kerafast、
软件：DocuSign、GraphPad、PyMOL、Craic、NextGene、Lighthouse data
进口流程
（此处以Amsbio为例，实际不同品牌不同产品类型所涉及流程稍有不同）
免责申明
1. 本公司并非以上各个品牌在中国区代理商，仅提供产品代理采购业务。
2. 本公司承诺所采购产品来自品牌厂家，并可提供相关进口证明。
3. 本公司保证全程采用官方指定运输条件进行产品运输。
4. 本公司对所委托进口产品品质不做任何担保，如遇质量问题，本公司可协助客户与品牌方进行协商处理售后问题。
5. 本公司因仅负责产品代购，因此不做任何技术支持，如采购，我们会提供产品相关的网页链接，可自行查看和下载产品相关的所有信息和技术资料。
代采服务咨询
如您有海外代采需求，请通过如下任意方式联系我们，并告知产品相关信息，我们将会在24小时之内和您联系。
邮箱：info@ebiomall.com
QQ：1570468124
手机：18915418616（微信同号）
电话：0512-67156496
或扫描微信联系我们
苏州蚂蚁淘生物科技有限公司简介
依托于集团公司深厚的资源和超过400家国内优质客户群体，生命科学领域一站式供应链体系，以及高风险生物材料进出口平台的优势，蚂蚁淘生物严格筛选国际创新且经过同行验证过的产品和技术，引入中国市场，开发、孵育和推广。
自公司成立以来，与海外一线品牌建立了长期的交流与合作关系，其中包括多家国际著名细胞和菌种保藏中心。仅2019年内，蚂蚁淘生物接受国内制药企业、科研机构、检测机构和大专院校等单位的委托，从近150个品牌引进各类生物试剂，其中不乏包括细胞株 ，慢病毒，人体组织切片，血液制品等特种试剂。公司与北京中关村联合创新（绿通北平台）建立了长期的交流与合作关系，可为国内客户提供进口代理业务，完成一站式前置审批、风险评估、检疫审批、清关查验、物流仓储等工作。
本公司特殊物品进口业务，严格遵守国家相关政策和法规流程，致力于为各单位提供更安全、更专业、更便捷的服务。
性能参数
产品详细描述
说明书(
bmeg_handbook.pdf)
Features:
-
Stable, high-yield protein expression in Bacillus megaterium
- Ideal for both small and large-scale protein production
- Tightly regulated and efficiently inducible xylose operon (up to 350-fold)
- No alkaline proteases activity even up to 5 hours after induction
- No endotoxins observed
- Versatile cloning (extended polylinker, additional BsrG I site*)
- Versatile production (intracellular or extracellular)
- Versatile purification (native, 6xHis-tag, Strep-tag, Strep/6xHis double-tag)
-
Removeable tag versions (for TEV or Xa proteases) available
- Compatible with all B. subtilis vectors
*BsrG I site is not included in all vectors.
The B. megaterium expression system provides a versatile and easy-to-handle tool for stable and high-yield protein production, both small and large scale.
B. megaterium has proven to be an excellent alternative host to E. coli for heterologous gene expression. Unlike other bacilli strains, proteolytic degradation by alkaline proteases is avoided. In addition, there are no endotoxins found in the cell wall.
High Protein Yield
As a result, protein yields are exceptionally high even if inexpensive substrates are used. For example, the proteins mutarotase (Mro) and glucose dehydrogenase (Gdh) have been accumulated up to 20% and 30% of the total soluble protein, respectively. Using the tightly regulated xylose operon, the genes were induced 130- to 350-fold without proteolysis.
Versatile System with a Wide Range of Vectors
MoBiTec provides a wide range of useful vectors for the B. megaterium system that are adaptable for most applications and protein purification methods. These include vectors carrying a secretion signal peptide sequence, a 6xHis-tag, a Strep-tag, and a Strep/6xHis double-tag. Additionally, all vectors contain the tightly regulated and highly inducible xylose operon promoter.
B. megaterium protoplasts specifically optimized for transformation
The protoplasts supplied by MoBiTec are from B. megaterium strain WH320 developed by Prof. Dr. W. Hillen at the Institute of Microbiology in Erlangen, Germany. These protoplasts are prepared according to an optimized protocol resulting in the highest transformation efficiencies.
For secretion vectors we offer protoplasts of strain MS941. Both strains are mutants of DSM319, where WH320 is a chemically mutant, while MS941 has a defined deletion in the gene of the major extracellular protease NprM.
Examples:
Selected Proteins successfully over-produced in Bacilli strains with our B. megaterium vectors:
- β-Galactosidase (LacZ)1
- Catabolite control protein (CcpA)2,3
- Clostridium difficile toxin A4
- Cobaltochelatase (CbiX)5
- Dextransucrase6
- Endolevanase (LevB)7
- Glucose dehydrogenase (GdhA)1
- Heat shock protein (HPr) from PTS (phosphotransferase sugar transport system)8
- Human single-chain urokinase-like plasminogen activator (rscuPA)1
- Levansucrase9
- Mutarotase (Mro)1
- Neopullulanase10
- Translocation ATPase of the preprotein translocase (SecA)11
- Trehalose repressor (TreR)12
