生物360邀您共享表观遗传学研究饕餮盛宴“第四届发育和疾病的表观遗传学上海国际研讨会”（2018年9月18-21日，上海），点击注册
http://i.bio360.net/MEET/2018epigenetics/sign.html
表观遗传学(Epigenetics)是论及决定细胞时代间基因组转录记忆的与DNA序列改变无关的信号,介导者和机制的学科。表观遗传事件通过对DNA和组蛋白的共价修饰,以转录的RNA和翻译的蛋白的方式,调节和功能化地展示编码在DNA序列中遗传的结构信息,继而产生在时空多维空间无限多样的表型。健康表观遗传稳态是确保高等生物发育过程中细胞分化和谱系化正常开展所依据的优态基因组表达的必要前提。基因组表观遗传信息界面的异常是包括肿瘤,代谢类和神经系统疾病在内的疾患的病因,病理学机制之一。
为了加大本次大会学术交流的力度,除了6个主题/36个25分钟报告以外,我们还安排了12个10分钟报告,后者是从两个时长1.5小时的墙报摘要者中遴选出来的。欢迎各位与会者积极报名并提交墙报摘要！
会议主题：
主题1.DNA修饰的化学和生物学
主题2.组蛋白修饰的化学和生物学
主题3.转录的化学生物学和表观调控
主题4.临床表观遗传学
主题5.染色质高级结构的化学和生物学
主题6.发育的表观遗传学
演讲嘉宾：
徐国良（中科院上海生命科学研究院）
报告题目：AvitaminC-derivedDNAmodification
http://i.bio360.net/MEET/2018epigenetics/customer.html
朱冰（中科院生物物理研究所）
报告题目：DynamicregulationofDNAmethylation
http://i.bio360.net/MEET/2018epigenetics/bingzhu.html
JamesShen（AcademiaSinica，Taipei）
报告题目：ActiveDNADemethylationbyVertebrateDNAMethyltransferases
http://i.bio360.net/MEET/2018epigenetics/james.html
伊成器（北京大学）
报告题目：Chemical-assistedSequencingofEpigeneticNucleicAcidModifications
http://i.bio360.net/MEET/2018epigenetics/chengqi.html
张鹍（UCSD)
报告题目：Single-cellmulti-omicanalysisofhumanorgans.
http://i.bio360.net/MEET/2018epigenetics/kunzhang.html
徐彦辉（复旦大学）
报告题目：StructuralInsightintodynamicregulationofDNAmethylation
http://i.bio360.net/MEET/2018epigenetics/yanhui.html
NaokoHattori（Japan）
报告题目：EpigenomeReprogrammingasaBasisforCombinationTherapy
http://i.bio360.net/MEET/2018epigenetics/naoko.html
刘峰（中科院动物所）
报告题目：EpigeneticRegulationofHematopoieticStemCellDevelopment
http://i.bio360.net/MEET/2018epigenetics/fengliu.html
陈玲玲（中科院上海生命科学研究院）
报告题目：THEDIVERSITYANDFUNCTIONOFLONGNONCODINGRNAS
http://i.bio360.net/MEET/2018epigenetics/lingling.html
沈晓骅（清华大学）
报告题目：Cis-actinglncRNAsintranscriptionandchromatinregulation
http://i.bio360.net/MEET/2018epigenetics/xiaohua.html
孙前文（清华大学）
报告题目：R-loop,thegeneralchromatinfeatureinArABIdopsisgenomes
http://i.bio360.net/MEET/2018epigenetics/qianwen.html
王泽峰（中科院上海生命科学研究院）
报告题目：Re-thinkingthecodingcapacityofnon-codingRNA.
http://i.bio360.net/MEET/2018epigenetics/zefeng.html
Hsueh-PingChu（NationalTaiwanUniversity)
报告题目：AlongnoncodingRNAintelomeremaintenance,generegulationandinter-chromosomalpairing.
http://i.bio360.net/MEET/2018epigenetics/hsueh.html
YutakaKondo（Japan）
报告题目：ImplicationofLongNon-codingRNAsinCancerBIOLOGy
http://i.bio360.net/MEET/2018epigenetics/yutaka.html
韩为东（301医院）
报告题目：Enhancedanti-tumoractivityofPD1blockadebyDNAdemethylatingagentintheclinic
http://i.bio360.net/MEET/2018epigenetics/weidong.html
JungKyoonChoi（Singapore）
报告题目：Functionalpredictionofcausalregulatoryvariantsidentifiesanovelautismgene
http://i.bio360.net/MEET/2018epigenetics/jungkyoon.html
陆星宇（上海）
报告题目：DNA5-HydroxymethylcytosinesfromCell-freeCirculatingDNAasDiagnosticBioMarkersforHumanCancers
http://i.bio360.net/MEET/2018epigenetics/xinyu.html
罗成（中科院上海药物研究所）
报告题目：Drugdiscoveryofprotein-proteininteractionsbytargetingepi-modificationsiteofuntargetableprotein
http://i.bio360.net/MEET/2018epigenetics/chengluo.html
李国红（中科院生物物理所）
报告题目：Dynamicregulationofhigher-orderchromatinstructuresingeneregulation
http://i.bio360.net/MEET/2018epigenetics/guohong.html
颉伟（清华大学）
报告题目：Reprogrammingofchromatinarchitectureinearlymammaliandevelopment
http://i.bio360.net/MEET/2018epigenetics/weixie.html
YijunRuan（JackonLab)
报告题目：Combinatorialmechanismsin3Dgenomefoldingandtranscriptionregulation
http://i.bio360.net/MEET/2018epigenetics/yijun.html
ShengZhong（UCSD)
报告题目：SystematicMappingofRNA-ChromatinInteractionsInVivo
http://i.bio360.net/MEET/2018epigenetics/zhongshen.html
ChandrimaDas（India）
报告题目：DecodingtheEpigeneticLandscapebytheHistoneReaders:Implicationsinhumandiseases
http://i.bio360.net/MEET/2018epigenetics/chandrima.html
Li-JungJuan（AcademiaSinica,Taipei)
报告题目：CROSSTALKOFN-A-ACETYLTRANSFERASEANDDNAMETHYLATIONINDEVELOPMENTANDDISEASE
http://i.bio360.net/MEET/2018epigenetics/lijung.html
汤富酬（北京大学）
报告题目：Single-cellmulti-omicssequencingofmouseearlyembryosandembryonicstemcells
http://i.bio360.net/MEET/2018epigenetics/fuchou.html
邓宏魁（北京大学）
报告题目：SmallMolecule-inducedCellFateReprogramming
http://i.bio360.net/MEET/2018epigenetics/hongkui.html
大会日程：
| 19th,Sept,2018 | |||
| 8:30-8:40 | Opening | ||
| I.ChemicalandBiologicalPerspectivesofDNAModificationsChairofthefirsthalfpart:KazuUshijima(Tokyo) | |||
| 8:40-9:05 | AvitaminC-derivedDNAmodification | GuoliangXu(AcademiaSinica,Shanghai) | |
| 9:05-9:25 | DynamicregulationofDNAmethylation | BingZhu(AcademiaSinica,Beijing) | |
| 9:25-9:50 | ActiveDNADemethylationbyVertebrateDNAMethyltransferases | JamesShen(AcademiaSinica,Taipei) | |
| 9:50-10:15 | Chemical-assistedSequencingofEpigeneticNucleicAcidModifications | ChengqiYi(PekingUniversity) | |
| 10:15-10:40 | Break+GroupPhotograph | ||
| Chairofthesecondhalfpart:FeiLan(FuDanUniversity) | |||
| 10:40-11:05 | Single-cellmulti-omicanalysisofhumanorgans | KunZhang(UCSD) | |
| 11:05-11:30 | StructuralInsightintodynamicregulationofDNAmethylation | YanhuiXu(FudanUniversity) | |
| 11:30-11:40 | EpigenomeReprogrammingasaBasisforCombinationTherapy | NaokoHattori(Tokyo,Japan) | |
| 11:40-11:50 | ShortTalk2 | ||
| 11:50-13:00 | Lunch | ||
| 13:00-14:30 | PostersessionI | ||
| II.ChemicalandBiologicalPerspectivesofhistonemodificationsChairofthefirsthalfpart:YoungjunKim(Korea,Seul) | |||
| 14:30-14:55 | StructureandFunctionofYEATSDomaininHealthandDisease | HaitaoLi(TsinghuaUniversity)， | |
| 14:55-15:20 | TheDynamicRegulationofHistoneMethylation | FeiLan(FudanUniversity) | |
| 15:20-15:45 | De-acetylationandEpigenomicregulation | UllasKolthur-Seetharam （TataInstitute，India） | |
| 15:45-16:10 | Metabolicregulationofgeneexpression | ZhiminLu(MDAnderson) | |
| 16:10-16:30 | TeaBreak | ||
| Chairofthesecondhalfpart:LijungJuan(AcademiaSinica,Taipei) | |||
| 16:30-16:55 | EpgeneticsandADIpogenesis:ImplicationsofHistonemodificationsLanguages | TapasK.Kundu(India) | |
| 16:55-17:20 | Crosstalkbetweenhistonemodificationsduringheterochromatinassembly | Jun-ichiNakayama(Japan) | |
| 20th,Sept,2018 | ||
| III.ChemicalandepigeneticregulationoftranscriptionChairofthefirsthalfpart:ShyamPRABHAKAR(Singapore) | ||
| 8:30-8:55 | R-loopsinphysiologyandpathology | XiangdongFu(UCSD) |
| 8:55-9:20 | EpigeneticRegulationofHematopoieticStemCellDevelopment | FengLiu(AcademiaSinica,Beijing) |
| 9:20-9:50 | TheDiversityandFunctionofLongNoncodingRNAs | LinglingChen(AcademiaSinica,Shanghai) |
| 9:50-10:15 | Cis-actinglncRNAsintranscriptionandchromatinregulation | XiaohuaShen(TsinghuaUniversity) |
| 10:15-10:40 | TeaBreak | |
| Chairofthesecondhalfpart:HongkuiDeng(PekingUniversity) | ||
| 10:40-11:05 | R-loop,thegeneralchromatinfeatureinArabidopsisgenomes | QianwenSun(TsinghuaUniversity) |
| 11:05-11:30 | Re-thinkingthecodingcapacityofnon-codingRNA | ZefengWang(AcademiaSinica，Shanghai) |
| 11:30-11:40 | AlongnoncodingRNAintelomeremaintenance,generegulationandinter-chromosomalpairing | Hsueh-PingChu(NationalTaiwanUniversity) |
| 11:40-11:50 | ShortTalk4 | |
| 11:50-13:00 | Lunch | |
| 13:00-14:30 | Postersession2 | |
| IV.ClinicalEpigeneticsChairofthefirsthalfpart:TapasKundu(India) | ||
| 14:30-14:55 | ImplicationofLongNon-codingRNAsinCancerBiology | YutakaKondo(NagoyaUniversity,Japan) |
| 14:55-15:20 | Enhancedanti-tumoractivityofPD1blockadebyDNAdemethylatingagentintheclinic | WeidongHan(301Hospital,Beijing); |
| 15:20-15:45 | Talk21 | TehBinTean(CancerCenter,Singapore), |
| 15:45-16:10 | Functionalpredictionofcausalregulatoryvariantsidentifiesanovelautismgene | JungKyoonChoi(Korea) |
| 16:10-16:30 | TeaBreak | |
| Chairofthesecondhalfpart:ZefengWang(AcademiaSinica) | ||
| 16:30-16:55 | DNA5-HydroxymethylcytosinesfromCell-freeCirculatingDNAasDiagnosticBiomarkersforHumanCancers | XingyuLu(Shanghai) |
| 16:55-17:20 | Drugdiscoveryofprotein-proteininteractionsbytargetingepi-modificationstateofuntargetableprotein | ChengLuo(AcademiaSinica，Shanghai) |
| 21st,Sept,2018 | ||
| V.Chemicalandbiologicalperspectivesofthehigher-orderchromatinstructureChairofthefirsthalfpart:Young-JoonKim(Korea) | ||
| 8:30-8:55 | Talk25 | Jun-ichiNakayama(Tokyo，Japan) |
| 8:55-9:20 | Dynamicregulationofhigher-orderchromatinstructuresingeneregulation | GuohongLi(AdademiaSinica,Beijing) |
| 9:20-9:45 | Reprogrammingofchromatinarchitectureinearlymammaliandevelopment | WeiXie(TsinghuaUniversity) |
| 9:45-10:10 | Combinatorialmechanismsin3Dgenomefoldingandtranscriptionregulation | YijunRuan(JacksonLab,USA) |
| 10:10-10:30 | TeaBreak | |
| Chairofthesecondhalfpart:LinglingChen(AcademiaSinica,Shanghai) | ||
| 10:30-10:55 | SystematicMappingofRNA-ChromatinInteractionsInVivo | ShengZhong(UCSD) |
| 10:55-11:20 | Talk30 | |
| 11:20-11:30 | DecodingtheEpigeneticLandscapebytheHistoneReaders:Implicationsinhumandiseases | ChandrimaDas |
| 11:30-11:40 | Shorttalk6 | |
| 11:40-13:00 | Lunch | |
| VI.DevelopmentalEpigeneticsChairofthefirsthalfpart:GuoliangXu(AcademiaSinica,Shanghai) | ||
| 13:00-13:25 | Talk31 | |
| 13:25-13:50 | CROSSTALKOFN-A-ACETYLTRANSFERASEANDDNAMETHYLATIONINDEVELOPMENTANDDISEASE | Li-JungJuan(AdademiaSinica,Taipei) |
| 13:50-14:15 | Single-cellmulti-omicssequencingofmouseearlyembryosandembryonicstemcells | FuchouTang(PekingUniversity) |
| 14:15-14:25 | Shorttalk7 | |
| 14:25-14:35 | Shorttalk8 | |
| 14:35-14:45 | Shorttalk9 | |
| 14:45-14:55 | Shorttalk10 | |
| 14:55-15:15 | TeaBreak | |
| Chairofthesecondhalfpart:XiangdongFu(UCSD) | ||
| 15:40-15:50 | ShortTalk11 | |
| 15:50-16:00 | ShortTalk12 | |
| 16:00-16:25 | Talk35 | |
| 16:25-16:50 | SmallMolecule-inducedCellFateReprogramming | HongkuiDeng(PekingUniversity) |
| 16:50-17:00 | Closing | |
欲实时把握表观遗传学理论、技术和应用的最新进展，请参加第四届发育和疾病的表观遗传学上海国际研讨会（2018年9月18-21日，上海）
会务组
联系人：张老师闫老师
邮箱：chris.zhang@bio360.net/event@bio360.net/
电话：021-59555696/18516613552/18512189851
