BiologicalActivity
Antagonistoftheatypicalimidazolinebindingsite(putativeI3receptor)ofpancreaticβ-cells.Selectivelyblocksefaroxan-inducedinsulinsecretioninvitroandinvivo.
CompoundLibraries
KU14RisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 214.27 |
| Formula | C13H14N2O |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 189224-48-4 |
| PubChemID | 4302964 |
| InChIKey | JCWVNNMJXQJVNC-UHFFFAOYSA-N |
| Smiles | CCC1(CC2=CC=CC=C2O1)C1=NC=CN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.43 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight214.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.67mL | 23.34mL | 46.67mL |
| 5mM | 0.93mL | 4.67mL | 9.33mL |
| 10mM | 0.47mL | 2.33mL | 4.67mL |
| 50mM | 0.09mL | 0.47mL | 0.93mL |
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ProductDatasheets
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