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Tocris/Prosaptide TX14(A)/5151/1/1 mg
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Tocris/Prosaptide TX14(A)/5151/1/1 mg
品牌 / 
Tocris
货号 / 
5151/1
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4000-520-616
Description:PotentGPR37andGPR37L1agoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentGPR37L1andGPR37agonist(EC50valuesare5and7nM,respectively).Stimulatessignalingthroughpertussistoxin-sensitiveGproteins.StimulatesERKphosphorylation.Protectsagainstcellularstress.PromotesmyelinlipidsynthesisandprolongscellsurvivalinbothSchwanncellsandoligodendrocytes;neuroprotectiveandglioprotective.

TechnicalData

M.Wt1579.72
FormulaC69H110N16O26
SequenceTXLIDNNATEEILY

(Modifications:Ala-2=D-Ala)

StorageStoreat-20°C
CASNumber196391-82-9
PubChemID16197909
InChIKeySMUKRAODILXPSW-SRWCCNGVSA-N
Smiles[H]N[C@@H]([C@@H](C)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1579.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.63mL3.17mL6.33mL
5mM0.13mL0.63mL1.27mL
10mM0.06mL0.32mL0.63mL
50mM0.01mL0.06mL0.13mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet