other brands: Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guavaproduct type: antibodyproduct name: phospho-MLKL (Ser358) Antibody Setcatalog: 17-10400quantity: 1 Setclonality: polyclonalhost: rabbitconjugate: nonconjugatedreactivity: humanapplication: western blot, immunohistochemistrymore info or order: EMD Millipore product webpagePublished Application/Species/Sample/DilutionReferenceimmunohistochemistry; human; loading ...; fig3aAl Lamki R, Lu W, Manalo P, Wang J, Warren A, Tolkovsky A, et al. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis. 2016;7:e2287 pubmedpublisher Background: Mixed lineage kinase domain-like protein (MLKL) is required for the execution of programmed necrosis. MLKL is a cell-permeable acrylamide compound that inhibits human, but not murine, MLKL adaptor function via covalent modification of Cys86. MLKL prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with further downstream effectors.ALT Names: Mixed lineage kinase domain-like protein;MLKLImmunogen: Linear peptide corresponding to the Protein Kinase Domain of phospho-MLKL (Ser358).Specificity: When used together and under the \"Recommended Usage” instructions, this antibody set will detect MLKL phosphorylated at Ser358.Package Size: 1 SetUses: Western BlottingStorage: Stable for 1 year at 2-8°C from date of receiptmore info or order: EMD Millipore product webpagebioscienceshelp@emdchemical.comhttps://www.emdmillipore.com888-854-3417headquarters: United StatesEMD Millipore is the Life Science division of Merck KGaA of Darmstadt, GermanyHundreds of New Antibodies in the areas of: Cancer Nuclear Signaling Apoptosis Cardiovascular Disease Developmental Biology Metabolic Disease Neurodegenerative Disease Cell BiologyView all the new antibodies at www.emdmillipore.com.