高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒- 威海金威斯生物科技有限公司
产品名称：高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒
英文名称：Soluble Lectin-like oxidized LDL Receptor 1 (LOX-1) (Human) Ultrasensitive ELISA Kit
产品编号：SK00006-08
规格：96 T
产品介绍：
美国爱威斯生物开发的高敏感性血凝素样氧化低密度脂蛋白受体-1（可溶性）(人)酶联试剂盒
High Sensitivity
Monoclonal Antibody Pair Formulated
Calibrator: human sLOX-1 Rec (NS0 derived)
Validated by western blot and ELISA
Alternative name: Oxidized Low-density Lipoprotein Receptor 1 (OLR1).Soluble LOX-1 is a new biomarker of cardiovascular research.Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis.
Citations:
Perla-Monserrat Madrigal-Ruíz, et al. Low CD36 and LOX-1 Levels and CD36 Gene Subexpression Are Associated with Metabolic Dysregulation in Older Individuals with Abdominal Obesity Journal of Diabetes ResearchVolume 2016, Article ID 5678946
Features
Size: 96 T
Standard Range: 7.8 ~ 500 pg/ml
Sensitivity: 5 pg/mlSpecificity: human soluble LOX-1 NS0 derived
Sample Type: serum or plasma
Dilution factor: N/A
Intra-CV: 4-6%
Inter-CV:8-10%
Data Sheet:PDF
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