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Neuromics/NABC1/RA19031/100 ug
2025-05-12
Type: Rabbit IgG
Applications: WB
E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like AssaysSpecies Reactivity: H
B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; AllFormat: Affinity Purified - liquid
Immunogen: Reacts with residues 532-550 [DTNSLQNGDKLQKRPEKRQ] of human NABC1. NABC1 is a 60 kDa protein; however it forms dimers, which are easliy detected in MCF-7 cells.
![\"Picture\"](\"https://www.ebiomall.com/images/neuromics/2017/A8x365fx66x1.jpg\")
A novel gene, Novel Amplified in Breast Cancer-1 (NABC1) is implicated in breast cancer development. Breast tumor lines that harbor amplification of the cancer-related amplicon 20q13.2 display high levels of the NABC1 protein compared to normal human fibroblasts or a breast cancer line that does not overexpress the NABC1 mRNA.
Image: Western Blot detection of NABC1 from 15 ug. MCF-7 cell lysates. Please note protein is detected at 60 kDa. A band at approximately 120 kDa is due to dimerization.
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