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Enzolifesciences/[pTyr15]Cdk1/cdc2 polyclonal antibody/ADI-905-704-100/100µg
2026-08-21
Product Specification:
| Alternative Name: | Cell division cycle 2, Cyclin-dependent kinase 1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the C-terminus of human cdc2/Cdk1 phosphorylated at Tyr 15. |
| UniProt ID: | P06493 |
| Species reactivity: | Human |
| Applications: | WB |
| Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~34kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins. |
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