Adipogen/Bentamapimod/SYN-1147-M010/10 mg-蚂蚁淘商城

新闻动态

Adipogen/Bentamapimod/SYN-1147-M010/10 mg

2025-06-19

More Information Product Details Synonyms Product Type Properties Formula MW CAS Purity Chemicals Appearance Solubility Declaration Other Product Data InChi Key Shipping and Handling Shipping Short Term Storage Long Term Storage Use/Stability Documents MSDS Product Specification Sheet Datasheet

AS-602801

Chemical

C₂₅H₂₃N₅O₂S

457.6

848344-36-5

≥95%

Solid.

Soluble in DMSO.

Manufactured by SynKinase.

Target: PDGFR | Kinase Group: RTK | Substrate: TyrosineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

XCPPIJCBCWUBNT-UHFFFAOYSA-N

AMBIENT

+4°C

-20°C

Stable for at least 2 years after receipt when stored at -20°C.

Download PDF

Bentamapimod (AS602801) is a novel and orally active c-Jun-N-Terminal Kinase Inhibitor highly specific for JNK kinases. The inhibitor Bentamapimod (AS602801) is a potent anti-inflammatory agent which has been shown to reduce the disease burden in several pre-clinical models for endometriosis, and has the potential to be effective in addressing the causes of post-operative abdominal adhesions. Pre-clinical data have demonstrated Bentamapimod to be an effective anti-inflammatory compound with anti-fibrotic properties. Bentamapimod (AS602801) showed good bioavailability in rats (F=50%). It does cross the blood brain barrier, with 98% brain penetration the drug has been well tolerated so far. Bentamapimod (AS602801) is a potent and selective JNK inhibitor with therapeutic potential in MS and fibrosis as well.Product References

Kinase targets and inhibitors for the treatment of airway inflammatory diseases: the next generation of drugs for severe asthma and COPD? I.M. Adcock & G. Caramori; BioDrugs 18, 167 (2004)

本文链接： https://www.ebiomall.cn/b285-adi/info-1528073668.html

免责声明本文仅代表作者个人观点，与本网无关。其创作性以及文中陈述文字和内容未经本站证实，对本文以及其中全部或者部分内容、文字的真实性、完整性、及时性本站不做任何保证或承诺，请读者仅作参考，并请自行核实相关内容。

没有了

Denaturing gradient gel electrophoresis (DGGE) approaches to...

1970-01-01

Sucrose Density Gradient Fractionation of Yeast Membranes - 蛋白提...

2006-08-04

Adipogen/Sericic acid/AG-CN2-0402-M005/5 mg

2020-07-09

Adipogen/5-Aminofluorescein/CDX-A0018-G001/1 g

2020-07-04

Free Webinar: Direct Radioisotopic Imaging