主页>应用>病原体减少治疗病原体减少治疗间充质干细胞免疫细胞可规模化制造

应用

病原体减少治疗间充质干细胞免疫细胞可规模化制造

病原体减少治疗

UltraGRO™ 产品含有细胞生长所需的丰富生长因子和细胞因子，被公认为是用于制造细胞和细胞产品的 FBS 的高效无异种替代品。

符合 cGMP考虑到病原体风险评估，所有 UltraGRO™ 产品均来自 FDA 许可的中心。每个捐赠者都经过采访、评估，并且使用 FDA 许可的传染病筛查测试对捐赠进行了测试。在确定捐赠适合使用之前，所有捐赠者的材料必须对所有经过筛查的病原体进行阴性测试。为了进一步最大限度地降低病原体传播的风险，FDA 许可的中心建立了详细的跟踪系统AventaCell 收到的所有材料都将经过验证和记录，然后保留一段保留期。如果捐赠在收集时检测为阴性，但捐赠者在下一次捐赠中检测为阳性，则库存保留期允许 FDA 许可的中心通知系统有机会帮助排除任何可疑单位用于制造。此外，我们的cGMP生产系统可防止生产过程中发生外来病原体污染。

此外，由于这些\"窗口期”供体在采集供体时无法进行筛选， AventaCell 采用最先进的伽马射线辐照工艺作为病毒灭活的病原体减少处理 (PRT)，以创建 UltraGRO™ GMP PRT 产品。成品的伽马射线照射会破坏病毒基因组的核酸并使其感染能力失活。我们已经验证了伽马射线照射工艺的有效性病毒灭活，同时对我们的 UltraGRO™GMP PRT 产品的效力和长期稳定性影响很小。

UltraGRO™ GMP PRT 产品提供更高的安全标准，最大限度地降低病原体污染风险，同时保留人类 MSC 的有效细胞培养性能、免疫细胞和其他适用于临床和商业应用的细胞类型。

主页>产品>UltraGRO™所有产品UltraGRO™-PURE GIUltraGRO™-Advanced GIUltraGRO™-PUREUltraGRO™-AdvancedUltraGRO™

产品

所有产品UltraGRO™-PURE GIUltraGRO™-PURE GI GMP 等级UltraGRO™-Advanced GIUltraGRO™-Advanced GI GMP 等级UltraGRO™-PUREUltraGRO™-PURE GMP 等级 UltraGRO™ -PURE 研究级UltraGRO™-AdvancedUltraGRO™-高级 GMP 级UltraGRO™-高级研究级UltraGRO™ UltraGRO™ GMP 级UltraGRO™ 研究级UltraGRO™ GMP 级

不含异种

细胞培养补充剂

GMP 级

UltraGRO™ 研究级

不含异种

细胞培养补充剂

研究级

1主页>产品>UltraGRO™-Advanced所有产品UltraGRO™-PURE GIUltraGRO™-Advanced GIUltraGRO™-PUREUltraGRO™-AdvancedUltraGRO™

产品

所有产品UltraGRO™-PURE GIUltraGRO™-PURE GI GMP 等级UltraGRO™-Advanced GIUltraGRO™-Advanced GI GMP 等级UltraGRO™-PUREUltraGRO™-PURE GMP 等级 UltraGRO ™-PURE 研究级UltraGRO™-AdvancedUltraGRO™-高级 GMP 级UltraGRO™-高级研究级UltraGRO™ UltraGRO™ GMP 级UltraGRO™ 研究级UltraGRO™-高级 GMP 级

非异种（原始材料）

去纤维蛋白原细胞培养补充剂

GMP 级

UltraGRO™-高级研究级

非异种（原始材料)

纤维蛋白原耗尽的细胞培养补充剂

研究级

1主页>产品>UltraGRO™-PURE所有产品UltraGRO™-PURE GIUltraGRO™-Advanced GIUltraGRO™-PUREUltraGRO™-AdvancedUltraGRO™

产品

所有产品UltraGRO™-PURE GIUltraGRO™-PURE GI GMP 等级UltraGRO™-Advanced GIUltraGRO™-Advanced GI GMP 等级UltraGRO™-PUREUltraGRO™-PURE GMP 等级 UltraGRO ™-PURE 研究级UltraGRO™-AdvancedUltraGRO™-高级 GMP 级UltraGRO™-高级研究级UltraGRO™ UltraGRO™ GMP 级UltraGRO™ 研究级UltraGRO™-PURE GMP 级

不含异种物质

去纤维蛋白原细胞培养补充剂

GMP 级

UltraGRO™-PURE 研究级

不含异种物质

纤维蛋白原耗尽的细胞培养补充剂

研究级

1主页>产品>UltraGRO™-Advanced GIAll 产品UltraGRO™-PURE GIUltraGRO™-Advanced GIUltraGRO™-PUREUltraGRO™-AdvancedUltraGRO™

产品

所有产品UltraGRO™-PURE GIUltraGRO™-PURE GI GMP 等级UltraGRO™-Advanced GIUltraGRO™-Advanced GI GMP 等级UltraGRO™-PUREUltraGRO™-PURE GMP 等级UltraGRO™-PURE 研究级UltraGRO™-AdvancedUltraGRO™-高级 GMP 级UltraGRO™-高级研究级UltraGRO™ UltraGRO™ GMP 级UltraGRO™ 研究级UltraGRO™-高级 GI GMP 级

非异种（原始材料）

伽马射线照射的纤维蛋白原耗尽细胞培养物

GMP 级

1主页>产品>UltraGRO™-PURE GIAll 产品UltraGRO™-PURE GIUltraGRO™-Advanced GIUltraGRO™-PUREUltraGRO™-AdvancedUltraGRO™

产品

所有产品UltraGRO™-PURE GIUltraGRO™-PURE GI GMP 等级UltraGRO™-Advanced GIUltraGRO™-Advanced GI GMP 等级UltraGRO™-PUREUltraGRO™-PURE GMP 等级UltraGRO™-PURE 研究级UltraGRO™-AdvancedUltraGRO™-高级 GMP 级UltraGRO™-高级研究级UltraGRO™ UltraGRO™ GMP 级UltraGRO™ 研究级UltraGRO™-PURE GI GMP 级

不含异种物质

伽马射线照射的纤维蛋白原耗尽细胞培养物

GMP 级

1主页>资源>出版物>>参考文献使用提示MSDSCoA&MSDS参考常见问题解答References111细胞治疗癌症治疗次2次单元次单元次1次单元次单元

出版物

使用提示MSDSCoA&MSDS参考常见问题解答出版物细胞外囊泡

1主页>资源>出版物>>参考文献使用提示MSDSCoA&MSDS参考常见问题解答References111细胞治疗癌症治疗次2次单元次单元次1次单元次单元

出版物

使用提示MSDSCoA&MSDS参考常见问题解答出版物细胞外囊泡

1主页>资源>出版物>>参考文献使用提示MSDSCoA&MSDS参考常见问题解答References111细胞治疗癌症治疗次2次单元次单元次1次单元次单元

出版物

使用提示MSDSCoA&MSDS参考常见问题解答出版物细胞外囊泡

1主页>资源>出版物>>参考文献使用提示MSDSCoA&MSDS参考常见问题解答References111细胞治疗癌症治疗次2次单元次单元次1次单元次单元

出版物

使用提示MSDSCoA&MSDS参考常见问题解答出版物细胞外囊泡

1主页>应用>病原体减少治疗间充质干细胞免疫细胞可规模化制造

应用

病原体减少治疗间充质干细胞免疫细胞可规模化制造

主页>应用>病原体减少治疗间充质干细胞免疫细胞可规模化制造

应用

病原体减少治疗间充质干细胞免疫细胞可规模化制造

CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa. 2-8°C; Avoid exposure to light; Do not freeze Please refer to product specific SDS Applications for relevant formats of this clone include -Flow Cytometry – Quality tested 1,5,10-18Immunohistochemistry-Frozen Sections – Reported in literature 2-8Immunohistochemistry-Paraffin Sections – Reported in literature 9Immunoprecipitation – Reported in literature 1Stimulation – Reported in literature 1 Chicken peripheral blood lymphocytes were stained with Mouse Anti-Chicken CD3-PE (SB Cat. No. 8200-09) and Mouse Anti-Chicken CD8α-FITC (SB Cat. No. 8220-02). Chicken peripheral blood lymphocytes were stained with Mouse Anti-Chicken CD3-PE (SB Cat. No. 8200-09) and Mouse Anti-Chicken CD8α-FITC (SB Cat. No. 8220-02). Mouse Anti-Chicken Monocyte/Macrophage-FITC 1. Chen CH, Ager LL, Gartland GL, Cooper MD. Identification of a T3/T cell receptor complex in chickens. J Exp Med. 1986;164:375-80. (Immunogen, FC, IP, Stim)2. Njenga MK, Dangler CA. Endothelial MHC class II antigen expression and endarteritis associated with Marek\'s disease virus infection in chickens. Vet Pathol. 1995;32:403-11. (IHC-FS)3. Tanimura N, Sharma JM. Appearance of T cells in the bursa of Fabricius and cecal tonsils during the acute phase of infectious bursal disease virus infection in chickens. Avian Dis. 1997;41:638-45. (IHC-FS)4. Zheng W, Yoshimura Y. Organ-specificity of estrogen effects on the induction of immunocompetent cells in the chicken. J Poult Sci. 2001;38:41-9. (IHC-FS)5. Sheela RR, Babu U, Mu J, Elankumaran S, Bautista DA, Raybourne RB, et al. Immune responses against Salmonella enterica serovar enteritidis infection in virally immunosuppressed chickens. Clin Diagn Lab Immunol. 2003;10:670-9. (FC, IHC-FS)6. Pantin-Jackwood MJ, Brown TP, Huff GR. Proventriculitis in broiler chickens: immunohistochemical characterization of the lymphocytes infiltrating the proventricular glands. Vet Pathol. 2004;41:641-8. (IHC-FS)7. Hansell C, Zhu XW, Brooks H, Sheppard M, Withanage S, Maskell D, et al. Unique features and distribution of the chicken CD83+ cell. J Immunol. 2007;179:5117-25. (IHC-FS)8. Schusser B, Collarini EJ, Yi H, Izquierdo SM, Fesler J, Pedersen D, et al. Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells. Proc Natl Acad Sci USA. 2013;110:20170-5. (IHC-FS)9. Solcan C, Solcan G, Cotea C. Immunotoxic action of ochratoxine A on lymphocytes from lymphoid tissues associated to gut mucosa in chickens. Bulletin UASVM Agriculture. 2010;67:283-90. (IHC-PS)10. Koskinen R, Göbel TW, Tregaskes CA, Young JR, Vainio O. The structure of avian CD5 implies a conserved function. J Immunol. 1998;160:4943-50. (FC)11. Conrad ML, Davis WC, Koop BF. TCR and CD3 antibody cross-reactivity in 44 species. Cytometry. 2007;71A:925-33. (FC)12. Janardhana V, Broadway MM, Bruce MP, Lowenthal JW, Geier MS, Hughes RJ, et al. Prebiotics modulate immune responses in the gut-associated lymphoid tissue of chickens. J Nutr. 2009;139:1404-9. (FC)13. Xue M, Shi X, Zhao Y, Cui H, Hu S, Cui X, et al. Effects of reticuloendotheliosis virus infection on cytokine production in SPF chickens. PLoS One. 2013;8(12):e83918. (FC)14. Peng X, Zhang K, Bai S, Ding X, Zeng Q, Yang J, et al. Histological lesions, cell cycle arrest, apoptosis and T cell subsets changes of spleen in chicken fed aflatoxin-contaminated corn. Int J Environ Res Public Health. 2014;11:8567-80. (FC)15. Vu Manh T, Marty H, Sibille P, Le Vern Y, Kaspers B, Dalod M, et al. Existence of conventional dendritic cells in Gallus gallus revealed by comparative gene expression profiling. J Immunol. 2014;192:4510-7. (FC)16. Pleidrup J, Dalgaard TS, Norup LR, Permin A, Schou TW, Skovgaard K, et al. Ascaridia galli infection influences the development of both humoral and cell-mediated immunity after Newcastle Disease vaccination in chickens. Vaccine. 2014;32:383-92. (FC)17. Laniewski P, Kuczkowski M, Chrząstek K, Woźniak A, Wyszyńska A, Wieliczko A, et al. Evaluation of the immunogenicity of Campylobacter jejuni CjaA protein delivered by Salmonella enterica sv. Typhimurium strain with regulated delayed attenuation in chickens. World J Microbiol Biotechnol. 2014;30:281-92. (FC)18. Dudek K, Bednarek D. Cellular immune response of pigeons in the conditions of endotoxin fever and pyrogenic tolerance. Pol J Vet Sci. 2011;14:127-33. (FC, Pigeon Reactivity)