Biosensis/Rabbit polyclonal antibody to human NOGO-A (1170-1192): Affinity purified/R-1611-100/100 µ
| Description | Neurite Outgrowth Inhibitor (NOGO) is a myelin associated neurite growth inhibitor found in oligodendrocyte and central nervous system (CNS) myelin membranes of the adult CNS. NOGO plays a role in blocking axonal regeneration in the CNS of higher vertebrates. At least 6 isoforms have been observed arising from alternative splicing. NOGO-A (Isoform 1) is specifically expressed in brain and testes and weakly expressed in heart and skeletal muscle. |
| Batch No. | See product label |
| Unit size | 100 µg |
| Antigen | A synthetic peptide corresponding to a region (1170-1192) from the C-terminus of human NOGO-A. |
| Antibody Type | Polyclonal |
| Other Names | RTN 4A; Nogo-A; RTN-xL; Reticulon-4; Neurite outgrowth inhibitor; Foocen; NSP; |
| Accession | Q9JK11 RTN4_RAT; |
| Produced in | Rabbit |
| Purity | Affinity purified on antigen column |
| Applications | Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/ml is recommended for WB. A concentration of 0.5-1.0 µg/ml is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Cross-reactivity | Rat (WB, IHC); Mouse (WB); expected to react with human due to sequence homology |
| Blast URL | Click here |
| Form | Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 |
| Reconstitution | Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material. |
| Storage | At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. |
| Expiry Date | 12 months after purchase |
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