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D-Mannitol是渗透性利尿剂，具有较弱的肾脏血管扩张活性。
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D-Mannitol Chemical Structure
CAS No. : 69-65-8
MCE 顾客使用本产品发表的科研文献
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纯度 & 产品资料
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参考文献
| Description |
D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator. Target: Others D(-)Mannitol is a sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of d-mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Mannitol can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. The compound has been used in studies as a stimulator of cecal microbial growth and cellulolytic activity in rabbits. It has been observed that mannitol can lower the fat digestibility and body fat accumulation in both normal and cecectomized rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b. Studies show that the mannitol operon is repressed by the transcription factor, mannitol operon repressor (MtlR) in Escherichia coli [1-3]. |
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| Molecular Weight |
182.17 |
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| Formula |
C₆H₁₄O₆ |
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| CAS No. |
69-65-8 |
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| SMILES |
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
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| Solvent & Solubility |
In Vitro:
H2O : ≥ 36 mg/mL (197.62 mM) * "≥" means soluble, but saturation unknown.
Preparing
Stock Solutions
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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