p-MEK-1/2 (S222/226) Antibody BS4734报价/价格-抗体 Bioworld- 巴傲得生物科技有限公司
A family of protein kinases located upstream of the MAP kinases and responsiblefor their activation has been identified. The prototype member of thisfamily, designated MAP kinase kinase, or MEK-1, specifically phosphorylatesthe MAP kinase regulatory threonine and tyrosine residues present in theThr-Glu-Tyr motif of ERK). A second MEK family member, MEK-2, resemblesMEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activatep38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5,whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylatesand activates the JNK signal transduction pathway. Phosphorylationon Ser/Thr by MAP kinase kinase kinases (RAF or MEKK1) positively regulatesthe kinase activity.蚂蚁淘在线声明：以上所展示的信息由企业自行提供，内容的真实性、准确性和合法性由发布企业负责。蚂蚁淘在线对此不承担任何保证责任。
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