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diatheva生物科技公司成立于2002年,总部位于意大利。是一家以使研究工业产品的私人研究机构。diatheva集中开发在该领域的研究和治疗应用:癌症,微生物感染和药理学。新产品的生产和销售(抗体,重组蛋白,免疫和SNP检测试剂盒)的诊断,在该领域的研究和治疗应用:癌症,微生物感染和药理学。diatheva有GMP授权设施设计的临床前和临床试验的研究与对艾滋病病毒和其他微生物病原体的免疫原,特别强调新原料药生产。diatheva是意大利能够*个设施提供GMP服务点播。
PBRT KITThe PBRT kit is intended for molecular typing of plasmid conferring drug resistance in Enterobacteriaceae.
The epidemiology of resistance plasmids is a major issue for the description of antimicrobial resistance diffusion. Plasmids can be categorized in families on the basis of their phylogenetic relatedness. The first classification scheme was based on the stability of plasmids during conjugation, a phenomenon called plasmid incompatibility (Inc). Incompatibility groups were defined as the inability of related plasmids to be propagated stably in the same cell line, thus only compatible plasmids can be rescued in transconjugants (Datta and Hughes, 1983; Inc groups are defined as reported by the Plasmid Section of the National Collection of Type Culture, Colindale London, UK). The Inc methodology cannot be easily applied to a large number of strains and its use has been limited by the laborious and time-consuming work required. The molecular identification and classification of plasmids by PCR is currently possible and it is based on the detection of plasmid replication controls (replicons), namely the portion of large, naturally occurring plasmids encoding the replicase gene (rep) and cis-acting regulatory elements, controlling plasmid DNA replication and copy number.
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