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Adipogen/Cytochalasin H/BVT-0447-M001/1 mg

  
  2024-04-28
  
More Information Product Details Synonyms Product Type Properties Formula MW CAS RTECS Source/Host Chemicals Purity Chemicals Appearance Solubility Identity Declaration InChi Key Shipping and Handling Shipping Short Term Storage Long Term Storage Handling Advice Use/Stability Documents MSDS Product Specification Sheet Datasheet
Paspalin P1; Kodocytochalasin 1; Cytochalasin O; NSC305222; 17-Deoxo-21-acetylzygosporin D
Chemical
C30H39NO5
493.6
53760-19-3
HA5306000
Isolated from Phomopsis sp.
≥98% (HPLC, NMR)
White solid.
Soluble in DMSO, methanol or acetone.
Determined by 1H-NMR and 13C-NMR.
Manufactured by BioViotica.
NAEWXXDGBKTIMN-CGCBHLOZSA-N
AMBIENT
+4°C
-20°C
After reconstitution protect from light at -20°C.
Stable for at least 1 year after receipt when stored at -20°C.
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  • Potent mycotoxin.
  • Phytotoxin.
  • Actin polymerization inhibitor. Used in actin polymerization and cytoskeletal reorganization studies.
  • Antibacterial, antifungal, nematocidal and antitumor compound.
  • Apoptosis inducer.
  • Anti-angiogenic agent.
  • Shows immunosuppressive activity.
  • Shown to modulate the CNS with potential anti-parkinson activity.
Product References
  • Toxicity and plant growth regulator effects of cytochalasin H isolated from Phomopsis sp.: J.M. Wells, et al.; Can. J. Microbiol. 22, 1137 (1976)
  • Structure of a new [11]cytochalasin, cytochalasin H or kodo-cytochalasin-1: M. A. Beno, et al.; JACS 99, 4123 (1977)
  • Effect of cytochalasins B & H on isoelectric focusing of chick embryonic neural retina cells: S. Ghaskadbi & L. Mulherkar; Indian J. Exp. Biol. 20, 869 (1982)
  • Effects of cytochalasin H on chick embryo explants cultured in vitro: S. Ghaskadbi, et al. Toxicology 33, 323 (1984)
  • Effects of cytochalasin and phalloidin on actin: J.A. Cooper; J. Cell Biol. 105, 1473 (1987)
  • A new immunosuppressive cytochalasin isolated from a Pestalotia sp.: N. S. Burres, et al.; J. Antibiot. 45, 1367 (1992)
  • Effects of cytochalasin H, a potent inhibitor of cytoskeletal reorganization, on platelet function: P. Natajaran, et al.; Platelets, 11, 467 (2000)
  • 1H and 13C NMR assignments of three nitrogen containing compounds from the mangrove endophytic fungus (ZZF08): Y. Tao, et al.; Magn. Reson. Chem. 46, 501 (2008)
  • Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa: S. Xu, et al.; Chem. Biodivers. 6, 739 (2009)
  • Characterization of kinase suppressor of Ras-1 expression and anticancer drug sensitivity in human cancer cell lines: S.M. Stoeger & K.H. Cowan; Cancer Chemother. Pharmacol. 63, 807 (2009)
  • Application of cytochalasin compound cytochalasin H in manufacture of the medicine for resisting Parkinsons disease: L. Shet, et al.; CN103816149 A20140528 (2014) (Patent)
  • Cytochalasin H, an active anti-angiogenic constituent of the ethanol extract of Gleditsia sinensis Thorns: J. Lee, et al.; Biol. Pharm. Bull. 37, 6 (2014)
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