Enzolifesciences/MYSM1 (human) polyclonal antibody/BML-PW0660-0100/100µl-蚂蚁淘商城

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Enzolifesciences/MYSM1 (human) polyclonal antibody/BML-PW0660-0100/100µl

2025-05-11

Product Specification:

Alternative Name:	Myb-like, SWIRM and MPN domain-containing protein 1

Host:	Rabbit

Immunogen:	Synthetic peptide corresponding to aa 665-679 of human MYSM1.

UniProt ID:	Q5VVJ2

Species reactivity:	Human

Applications:	WB

Recommended Dilutions/Conditions:	Western Blot (1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Purity Detail:	Purified by salt precipitation.

Formulation:	Liquid. In PBS containing 0.01% sodium azide.

Use/Stability:	Stable for at least 1 year after receipt when stored at -20°C. Dilute with PBS, pH 7.2-7.4, containing 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used). Store diluted antibody at +4°C, do not freeze and use within 1 month.

Handling:	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.

Shipping:	Shipped on Blue Ice

Short Term Storage:	+4°C

Long Term Storage:	-20°C

Scientific Background:	MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1) is a JAMM domain containing zinc metalloprotease that acts a deubiquitinylating enzyme specific for mono-ubiquitinylated histone H2A. MYSM1 acts by coordinating histone acetylation and deubiquitination, and destabilizing the association of linker histone H1 with nucleosomes. In addition, MYSM1 participates in transcriptional regulation events in androgen receptor-dependent gene activation. Levels of monoubiquitinylated H2A are dramatically decreased in prostate tumors, suggesting MYSM1 expression may serve as a cancer marker.