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Enzolifesciences/IRAK-1 polyclonal antibody/ADI-905-709-100/100µg
2025-05-11
Product Specification:
| Alternative Name: | Interleukin-1 receptor-associated kinase 1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human IRAK-1. |
| UniProt ID: | P51617 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ICC, IP, WB |
| Purity Detail: | DEAE purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression. |
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