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MACS/Anti-DO11.10 TCR pure – functional grade, mouse (clone: KJ1-26)/130-095-379/

  
  2025-08-01
  
For research use onlyContent: 500 µg in 0.5 mL

Overview

The DO11.10 mouse model is a valuable tool for studies of T cell immigration, immunoregulation, development, activation, and function. The KJ1-26 monoclonal antibody reacts with the T cell receptor (TCR) expressed on lymphocytes of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. The DO11.10 TCR is specific for the chicken ovalbumin (OVA) peptide (323-339) in the context of I-A[d] major histocompatibility (MHC) molecules. Transgenic DO11.10 T cells also recognize OVA peptide from jungle fowl and turkey in the presence of A20-1.11, the H-2d-bearing, antigen-presenting B cell lymphoma.

Applications

Anti-DO11.10 TCR pure - functional grade antibody is suited for functional assays, for example, blocking of antigen response of DO11.10 T cell hybridoma.

Technical data

Antigen DO11.10 TCR
Clone KJ1-26
Isotype mouse IgG2a
Isotype control
Alternative names of antigen TCRA, Tcralpha
Entrez Gene ID 21473
Molecular mass of antigen [kDa]
Cross-reactivity
Distribution of antigen T cells
Endotoxin level Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
Product format Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
Fixation
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates pure

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