
- Description
- Additional
Description
Details
Description:Mouse monoclonal antibody to human Interferon-gamma (IFN-γ)
Purification: Protein G affinity purified
Target Protein: HumanIFN-γ
Immunogen: Purified recombinant humanIFN-γ
Fusion Myeloma: Sp2/0-Ag14
Specificity:This antibody recognizes both recombinant and native human IFN-γ.
Species Reactivity: Human, other species not tested
Host / Isotype: Mouse, IgG1 Kappa
Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.
Storage: Store at -20oC
Research Area:Pro-inflammatory cytokine, anti-tumour and anti-viral immunity
Background:
IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL), effector T cells once antigen-specific immunity develops. IFN-γ stimulates its own expression and up-regulates other genes to stimulate and modulate immunity mainly through the Jak-Stat signalling pathway. It promoters T helper 1 differentiation and cell associated immunity, and also suppresses T helper 2 differentiation and humoral immunity.
IFN-γ is a potent macrophage activator. It binds to macrophage in conjugation with CD40, causing the macrophage to produce elevated amounts ofMHCmolecules. It also stimulates the production of antigen-processing associated transporters and enzymes.
IFN-γ is critical for anti-tumour and anti-viral immunity.
Applications:
ELISA:In indirect ELISA, the antibody reacts with recombinant IFN-γ coated plate at 0.1ng/mL of antibody concentration.
Western Blot: This antibody, used at a concentration of 0.5mg/mL, will allow visualization of 100ng/lane of IFN-γ.
References: If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.
Additional
Additional Information
Product Specificity | mAb anti-Human IFN-γ, 165 |
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Application | EIA, WB |
Size | 0.1 mg |
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2.β-内酰胺类青霉素(阿莫西林、氨苄西林、羧苄西林) 头孢菌素、碳青霉烯类、头霉素、单内酰环类、β-内酰酶抑制剂、甲氧青霉素类
3.大环内酯类 红霉素、白霉素(吉他霉素)、罗红霉素、阿奇霉素、克拉霉素、乙酰螺旋霉素、麦迪霉素、交沙霉素等
4 酰胺醇类:包括氯霉素、甲砜霉素等
5 四环素类:包括四环素、土霉素(强力霉素)、金霉素等
6 林可酰胺类 克林霉素、林可霉素
7.糖肽类抗生素: 比如万古霉素、替考拉宁
8 抗真菌抗生素:如灰黄霉素、两性霉素B
9 抗肿瘤抗生素:如丝裂霉素、放线菌素D、博莱霉素、阿霉素等
10 具有免疫抑制作用的抗生素如环孢霉素
11 多磷类抗生素:如磷霉素

