BiologicalActivity
Antitumoragentthatformsplatinum-DNAadducts.Causesintra-andinterstrandDNAcrosslinksblockingDNAreplicationandtranscription.EnhancesrADIation-inducedsingle-strandDNAbreakageanddisplayslowernephrotoxicitythananalogcisplatin(Cat.No.2251).
TechnicalData
| M.Wt | 371.25 |
| Formula | C6H12N2O4Pt |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 41575-94-4 |
| PubChemID | 10339178 |
| InChIKey | OLESAACUTLOWQZ-UHFFFAOYSA-L |
| Smiles | O=C(C21CCC2)O[Pt-2]([NH3+])([NH3+])OC1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.28 | 25 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight371.25.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.69mL | 13.47mL | 26.94mL |
| 5mM | 0.54mL | 2.69mL | 5.39mL |
| 10mM | 0.27mL | 1.35mL | 2.69mL |
| 50mM | 0.05mL | 0.27mL | 0.54mL |
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