BiologicalActivity
ReversIBLeinhibitorofvesiculartraffickingbetweenendoplasmicreticulumandGolgiapparatus.ModifiesGolgiADP-ribosylationfactor(ARF)1GTPaseactivityandinhibitsexocytosis(IC50~20mM).Hassimilar,butnotidentical,actiontobrefeldinA(Cat.No.1231).
CompoundLibraries
Exo1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 273.26 |
| Formula | C15H12FNO3 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 461681-88-9 |
| PubChemID | 310557 |
| InChIKey | KIAPWMKFHIKQOZ-UHFFFAOYSA-N |
| Smiles | COC(=O)C1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.33 | 100 | |
| ethanol | 6.83 | 25mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight273.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.66mL | 18.3mL | 36.6mL |
| 5mM | 0.73mL | 3.66mL | 7.32mL |
| 10mM | 0.37mL | 1.83mL | 3.66mL |
| 50mM | 0.07mL | 0.37mL | 0.73mL |
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