Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All
CD4isacell-surfaceglycoproteinfoundonthematurehelperTcellsandimmaturethymocytes,aswellasonmonocytesandmacrophages.(SomecytotoxicTcellshaveCD4proteinaswell.)Normally,about65%ofTcellsinthebloodareCD4+(haveCD4proteinprotrudingfromtheirmembrane).AmatureTcellwitheitherhaveCD4orCD8,butnotboth.DuringonestageofdevelopmentTcellsdevelopCD4andCD8receptors,buttheyeventuallyaredifferentiatedinthethymusandbecomemorespecialized.
Image:CD4structureandsequence
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