- Description
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Description
Details
Description:Biotin conjugated mouse monoclonal antibody to C-terminal of amyloid beta peptide 42 (Aβ42)
Purification:Protein G affinity purified
Product Type:Tracer antibody in matched antibody pair, biotin conjugated
Target Protein:C-terminal of amyloid beta peptide 42
Immunogen:KLH conjugated to a short peptide (MVGGVVIA) with amino acid sequence corresponding to the C-terminal of Aβ42
Fusion Myeloma:Sp2/0-Ag14
Specificity:This antibody recognizes the C-terminal sequence (MVGGVVIA) of Aβ42 and full length Aβ42.
Cross-Reactivity:The antibody does not cross react with amyloid beta peptide 40 in dot blotting and ELISA. Cross-reactivity to amyloid beta peptide 43 is less than 1% in ELISA.
Species Reacitvity:Human and other primates; mouse, rat
Host / Isotype: Mouse, IgG2b Kappa
Storage BufferFormulation:0.01M PBS, pH 7.0 ± 0.1 in 1% gelatin and 0.1% proclin-300
Storage: Store at -20oC. Avoid repeated freeze and thaw cycles.
Research Area:Aging and neurodegenerative diseases
Background:
Amyloid beta peptide 42 (Aβ42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer’s disease. Aβ42 and Aβ40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Aβ42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Aβ42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Aβ42 contributes to the pathogenesis of Alzheimer’s disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer’s disease. Another is that the neurotoxicity of Aβ42 oligomer is the cause of the disease.
Application:
ELISA:In combination with capturer anti-amyloid peptide N-terminal antibody (mAb clone NT 5B8, Cat. No.: MO-M40094D) and avidin-HRP conjugate, this biotin conjugated antibody can detect Aβ42 in Sandwich ELISA assay.
References:
If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.
Additional
Additional Information
| Product Specificity | mAb anti-Amyloid β Peptide 42, CA9 10C11, Tracer (Biotin) |
|---|---|
| Application | EIA |
| Size | 0.1 mL |
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二是镜检染色观察计数，破碎完全的基本看不到完整的菌体，都是细胞碎片
三是测菌液的电导率，根据电导率大小来判断。
其他诸如设置工作时间，定时，脉冲，连续等，随意，无要求；使用完毕放回干燥清洁的保管箱或工作台；
使用任何产品都要保持良好的使用习惯，注意保养，可提高使用寿命，就跟电视、电脑一样的。
主机型号：Biosafer950E
工作频率范围：20-25KHz频率自动跟踪
功率调节范围：2-99%连续可调
工作时间：0-999(s/m/h/t)
间隙时间：0.1-99.9s
工作计时方式：正序/倒序
温度保护设定：有
超声时间：0.1-99.9s
功率振幅显示：有
工作模式：间隙/连续/手动模式
通讯接口：RS485 RS232 PC端软件
功率：950W
标配变幅杆：Ф6mm
破碎量：0.5-600ml可选配变幅标：Ф2、Ф3、Ф10
