
- Species ReactivityMouse
- SpecificityDetects mouse MUP-1 in direct ELISAs.
- SourceMonoclonal Mouse IgM Clone # 663323
- PurificationProtein A or G purified from hybridoma culture supernatant
- ImmunogenMouse MUP-1 synthetic peptide
Accession # NP_112465 - FormulationLyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
- LabelUnconjugated
- Immunocytochemistry8-25 µg/mLSee below
- ReconstitutionSterile PBS to a final concentration of 0.5 mg/mL.
- ShippingThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
- Stability & StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
- Long Name:Major Urinary Protein 1
- Entrez Gene IDs:17840 (Mouse)
- Alternate Names:Ltn-1; Lvtn-1; major urinary protein 1; major urinary protein 10; major urinary protein 7; MUP 1; Mup1 major urinary protein 1; MUP1; MUP-1; Mup10; Mup7; Mup-a; Up-1
Background:
Major urinary protein 1 (MUP-1) is a 20 kDa lipocalin family glycoprotein that is secreted by the liver into the circulation and then excreted in the urine of male mice. Its beta -barrel structure with an internal hydrophobic cavity enables MUP-1 to serve as a carrier for a variety of pheromones. In the circulation, MUP-1 promotes energy expenditure, mitochondrial biogenesis, and oxidative function, and it inhibits hepatic glucose production, triglyceride accumulation, glucose intolerance, and insulin resistance. MUP-1 is downregulated in the liver and circulation of diabetic obese mice.
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