Description

MethoxyPEGSuccinimidylCarboxymethylEsterforaminePEGylation,withsuperiorqualityspecificationof ≥95%Substitution.

JenKemTechnology’sMethoxyPEGSuccinimidylCarboxymethylEster (MethoxyPEGNHSorMethoxyPEGSCM)isahighqualityaminereactivePEGproductwithastablenon-degradablelinkerbetweenthePEGpolymericchainandtheNHSester.MethoxyPEGSuccinimidylCarboxymethylEsterreactswiththeaminegroupoflysine(s)atroomtemperatureinlessthan1hratpH7-8.Shorter hydrolysishalflifeofM-PEG-SCMensuresmaximumselectivitytowardsmoststericallyavailableaminegroups.

JenKemTechnologyoffersMethoxyPEGSCMEster withMW2kDa (M-SCM-2000),MW3kDa(M-SCM-3000),MW5kDa(M-SCM-5000),MW10kDa(M-SCM-10K),MW20kDa(M-SCM-20K),MW30kDa(M-SCM-30K),MW35kDa(M-SCM-35K)andMW40kDa(M-SCM-40K),in1gand10gpackingsizes. DifferentMWofMethoxyPEGSCM Esterproductsmaybeavailablebycustomsynthesis,pleaseemailus attech@jenkemusa.comfordetailsoncustomPEGs.OtherlinearNHSestersareavailable–pleaseselectother stablelinkerNHSPEGs,or cleavablelinkerNHSPEGs.JenKemTechnology providesrepackagingservicesforanadditionalfee,pleasecontactusifyourequireadifferentpackagesizethanourcatalogselection.

BulkPEGsandGMPgradePEGsaremade-to-order.Pleasecontactus forbulkpricing.

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References:

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Foundedin2001byexpertsinPEGsynthesisandPEGylation,JenKemTechnologyspecializesexclusivelyinthedevelopmentandmanufacturingofhighqualitypolyethyleneglycol(PEG)productsandderivatives,andrelatedcustomsynthesisandPEGylationservices.JenKemTechnologyisISO9001andISO13485certified,andadherestoICHQ7AguidelinesforGMPmanufacture.TheproductionofJenKem®PEGsisback-integratedtoin-housepolymerizationdirectlyfromethyleneoxide,enablingfaciletraceabilityforregulatedcustomers.JenKemTechnologycaterstothePEGylationneedsofthepharmaceutical,biotechnology,medicaldeviceanddiagnostics,andemergingchemicalspecialtymarkets,fromlaboratoryscalethroughlargecommercialscale.