Product Type | Blocking Peptide |
Units | 50 µg |
Species reactivity | Human |
Application | Functional Inhibition |
BackgroundAcetylation of the tail of histone is known to cause chromatin to adopt a more ÔopenÕ 3D conformation, allowing trans factors grerater access to DNA. Histone acetyltransferases (HATs), complexes interact with sequence-specific activator proteins and target specific genes. In addition to histones, HATs acetylate non-histone proteins, implicating them in a wide variety of regulartory roles for these enzymes. By comparison, histone deacetylation promotes a more ÔclosedÕ chromatin conformation and in general leads to repression of gene activity. Mammalian histone deacetylases are divided into three classes on the basis of their similarity to various the yeast deacetylases. Class I (HDACs 1, 2, 3 and 8) related to the yeast Rpd3-like proteins, class II (HDACs 4, 5, 6, 7, 9 and 10)related to yeast Hda1-like proteins and class III related to the yeast protein Sir2. Inhibitors of HDAC have enormous potential as cancer therapeutic agents.
Product
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Concentration: See vial for concentration
ApplicationsBlocking peptide for use with HDAC1 antibodies (Cat. Nos. X1847P & X1879P).
Functional Analysis: Antibody Function Blocking
StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: Products are stable for one year from purchase when stored properly
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Protein Reference(s)
Database Name: UniProt
Accession number: Q13547
Species Accession: Human
Safety Datasheet(s) for this product:NM_Sodium Azide/wp-content/uploads/SDS/Antibody SDS with Sodium Azide Noridic-MUbio.pdf
ebiomall.com
>
>
>
>
>
>
>
>
>
>
>
>
如果使用抗生素,到出栏会有残留
无抗饲料可以使用宝积饲料
全程无抗
促进生长
促进生长
预防疾病
大量使用抗生素引起药物残留。实用药物残留的动物源食品能够导致肠道菌群失调,致病菌大量繁殖,给人类健康带来危害,抗生素的残留及耐药性对公共卫生安全的威胁也愈演愈烈,在食品安全日益突出的今天,消费者对鸡蛋的安全问题更加重视。对于无抗动物产品、优质鸡蛋的需求量逐渐增加。生产绿色、安全、无抗蛋品已成为社会的主要要求,也是蛋鸡业持续发展的必然选择。
基本原则
健康的鸡不会(必)用抗生素,不用抗生素能否养出健康的鸡?
蛋鸡品种差异较大、营养不均衡、环境应激、疾病等导致蛋壳破损严重,鸡舍卫生条件差及一些肠道疾病通常会导致粪污污染加剧,鸡蛋易被微生物污染。如不使用抗生素会导致鸡只大量死亡,在实际生产过程中养殖户会不间断地使用抗生素进行蛋鸡保健和治疗。
无抗必须改变和升级
最小限度疾病(MD)种鸡群,硬件上的温湿环境有害气体与生物的全面控制,基于群体的防疫体系与健康疾病管理,基于科学的程序化的养鸡生产。在养殖管理方面,鸡群温度控制在13~24℃,空气湿度55%~65%,并有新鲜清洁的空气,光照强度维持在10~20 LX,避免低光照强度、缩短光照时间及任意更改光照时间,充分发挥蛋鸡的生产潜能;日常管理工作要保持鸡舍人员的相对稳定,定期检测鸡群的体重,观察过肥、过瘦鸡群的比例,及时调整饲喂计划,及时淘汰;避免陌生人或动物闯入鸡舍,减少停水、停电、称重、高温等因素引起的应激,避免管理不当导致蛋鸡产蛋期过早结束,提高养殖场的经济效益。
无抗生素养殖
绝对不是用某种或几种物质替代掉抗生素,而必须进行系统的思考,对养殖的软硬件体系进行设计与升级。营养方面,配方要稳定,适宜日粮营养浓度,选取原料时充分考虑霉菌毒素的影响,在蛋鸡日粮中通过添加维生素(VA、VD3、VE)、微量元素(有机铁、有机锌)、微生态制剂(寡聚糖、益生菌、酵母培养物)、复合酶制剂、植物提取物及植物精油(茶多酚、苜草素、异黄酮、桑叶粉、银杏叶提取物)来调控蛋鸡对营养物质的吸收和利用,从而提高蛋鸡的生产性能。无抗养殖要摒弃传统养殖方法,寻找新的养殖思路。驰骋祥无抗保健专家生产的“养殖安”能够很好的解决蛋鸡在无抗生产中所需的营养浓度,产品能量高,耗料少;抗应激强,死淘少。
市 场
鸡蛋营养均衡,现代膳食中的蛋白质和维生素主要来源于鸡蛋,无抗鸡蛋是老人、孕妇、小孩的首选,市场需求较大;无抗鸡蛋拥有广阔的前景,经过有机认证的无抗鸡蛋价格是传统鸡蛋价格的2~2.5倍。
禽流感新常态下,如何防控;驰骋种禽疫病防控专家魏老师建议使用药物预防禽流感:
①蛋鸡、种鸡:每间隔30天使用“驰骋芪贞颗粒或双黄连粉”+驰骋EAD乳液+养殖安混合使用;一个疗程(3-4天)
②白羽肉鸡:每间隔10天使用“驰骋芪贞颗粒或双黄连粉”+驰骋EAD乳液+养殖安混合使用。一次使用4天。抗菌药物最佳选择“好得快或替嘉康”,可以配合使用达到预防或治疗气囊炎的发生。
③种鸭鹅、种鹅、肉鸭鹅、肉鹅:每月间隔20天使用“驰骋芪贞颗粒或双黄连粉 +驰骋EAD乳液+养殖安混合使用;一个疗程(4-5天)
催肥效果很不错的