BiologicalActivity
BiP(Hsp70-5)ERchaperoneinducer;inducesBiPexpressioninvitroandinvivo.ProtectsagainstER-stressinducedcelldeathinneuronalandretinalcelllines.Alsoprotectsagainstischaemia-inducedhippocampalcelldeathinvivo.
TechnicalData
| M.Wt | 209.22 |
| Formula | C9H7NO3S |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 101714-41-4 |
| PubChemID | 16656807 |
| InChIKey | SVFLBLCWKKQKDW-UHFFFAOYSA-N |
| Smiles | O=C(CSC#N)C1=CC=C(O)C(O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.92 | 100 | |
| ethanol | 20.92 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight209.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.78mL | 23.9mL | 47.8mL |
| 5mM | 0.96mL | 4.78mL | 9.56mL |
| 10mM | 0.48mL | 2.39mL | 4.78mL |
| 50mM | 0.1mL | 0.48mL | 0.96mL |
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