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Tocris/8-Bromo-cGMP, sodium salt/1089/50/50 mg
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Tocris/8-Bromo-cGMP, sodium salt/1089/50/50 mg
品牌 / 
Tocris
货号 / 
1089/50
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4000-520-616
Description:cGMPanalog;activatesPKG
ChemicalName:8-Bromoguanosinecyclic3',5'-monophosphatesodiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

MembranepermeablecGMPanalogthatactivatesproteinkinaseG(PKG).4.3-foldmorepotentthancGMPinactivatingPKG1αandpromotesrelaxationoftrachealandvascularsmoothmuscletissueinvitro.

TechnicalData

M.Wt446.09
FormulaC10H10BrN5NaO7P
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber51116-01-9
PubChemID23702959
InChIKeyZJRFCXHKYQVNFK-YEOHUATISA-M
Smiles[Na+].[H][C@@]12COP([O-])(=O)O[C@@]1([H])[C@@H](O)[C@@H](O2)N1C(Br)=NC2=C1NC(N)=NC2=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water44.61100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight446.09.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.24mL11.21mL22.42mL
5mM0.45mL2.24mL4.48mL
10mM0.22mL1.12mL2.24mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet