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Tocris/G-Protein antagonist peptide/1931/1/1 mg
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Tocris/G-Protein antagonist peptide/1931/1/1 mg
品牌 / 
Tocris
货号 / 
1931/1
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数    量:
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4000-520-616
Description:InhibitsGproteinactivationbyGPCRs
AlternativeNames:GPAnt-2
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SubstanceP-relatedpeptidethatinhibitsbindingofGproteinstotheirreceptors.CompetitivelyandreversIBLyinhibitsM2muscarinicreceptoractivationofGiorGoandinhibitsGsactivationbyβ-adrenoceptors.

TechnicalData

M.Wt1093.27
FormulaC57H64N12O9S
SequenceXQWFWWM

(Modifications:X=Glp,Trp-3=Trp-5=Trp-6=D-Trp,Met-7=C-terminalamide)

StorageDesiccateat-20°C
CASNumber143675-79-0
PubChemID71308571
InChIKeyWSYRBHQWMXTCHQ-SFIKJRKMSA-N
Smiles[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1093.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.91mL4.57mL9.15mL
5mM0.18mL0.91mL1.83mL
10mM0.09mL0.46mL0.91mL
50mM0.02mL0.09mL0.18mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet