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Description:InhibitsGproteinactivationbyGPCRs
AlternativeNames:GPAnt-2
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
SubstanceP-relatedpeptidethatinhibitsbindingofGproteinstotheirreceptors.CompetitivelyandreversIBLyinhibitsM2muscarinicreceptoractivationofGiorGoandinhibitsGsactivationbyβ-adrenoceptors.
TechnicalData
M.Wt | 1093.27 |
Formula | C57H64N12O9S |
Sequence | XQWFWWM (Modifications:X=Glp,Trp-3=Trp-5=Trp-6=D-Trp,Met-7=C-terminalamide) |
Storage | Desiccateat-20°C |
CASNumber | 143675-79-0 |
PubChemID | 71308571 |
InChIKey | WSYRBHQWMXTCHQ-SFIKJRKMSA-N |
Smiles | [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto2mg/mlinDMSO |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1093.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.91mL | 4.57mL | 9.15mL |
5mM | 0.18mL | 0.91mL | 1.83mL |
10mM | 0.09mL | 0.46mL | 0.91mL |
50mM | 0.02mL | 0.09mL | 0.18mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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