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Description:Inhibitorofβγsignaling
ChemicalName:3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one
Purity:≥97%
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InhibitorofGproteinβγsubunit-dependentsignaling.BlocksPI3-kinaseandRac1activationinHL60cellsandchemotaxisinHL60differentiatedcells.
TechnicalData
M.Wt | 364.31 |
Formula | C20H12O7 |
Storage | Storeat-20°C |
Purity | ≥97% |
CASNumber | 2103-64-2 |
PubChemID | 73685 |
InChIKey | PHLYOKFVXIVOJC-UHFFFAOYSA-N |
Smiles | OC1=CC=C(C(C(C=CC=C5)=C5C(O4)=O)4C(C=CC(O)=C3O)=C3O2)C2=C1O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 27.32 | 75 | |
ethanol | 3.64 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight364.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.74mL | 13.72mL | 27.45mL |
5mM | 0.55mL | 2.74mL | 5.49mL |
10mM | 0.27mL | 1.37mL | 2.74mL |
50mM | 0.05mL | 0.27mL | 0.55mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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