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Description:SelectiveinhibitorofOXE-RGβγsignaling
ChemicalName:N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Oxoeicosanoidreceptor1(OXE-R)modulator.SelectivelyinhibitsGβγbutnotGαisignalinguponactivationoftheGαi-βγheterotrimerbyOXE-R.InhibitsGβγ-mediatedopeningofGIRK1/2channelsinHEK293cells.
CompoundLibraries
Gue1654isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 447.6 |
Formula | C23H17N3OS3 |
Storage | Storeat+4°C |
Purity | ≥97%(HPLC) |
CASNumber | 397290-30-1 |
PubChemID | 5066134 |
InChIKey | UFOBDFMYJABXGK-UHFFFAOYSA-N |
Smiles | O=C(C(C5=CC=CC=C5)C4=CC=CC=C4)NC(S3)=NC1=C3C(SC(SC)=N2)=C2C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 22.38 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight447.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.23mL | 11.17mL | 22.34mL |
5mM | 0.45mL | 2.23mL | 4.47mL |
10mM | 0.22mL | 1.12mL | 2.23mL |
50mM | 0.04mL | 0.22mL | 0.45mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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