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![Tocris/[D-Trp<sup>7,9,10</sup>]-Substance P/1884/1/1 mg](images/201712/1512520078951260693.jpg)
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Description:InhibitsM1AChreceptoractivationofGq/11
AlternativeNames:GPAnt-2analog
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
SubstancePanalogthatinhibitsactivationofGq/11byM1muscarinicAChreceptors.DoesnotinhibitGi/oactivationbyM2AChreceptors.
TechnicalData
M.Wt | 1588.89 |
Formula | C79H105N21O13S |
Sequence | RPKPQQWFWWM (Modifications:Trp-7,Trp-9,Trp-10=D-Trp,Met-11=C-terminalAmide) |
Storage | Storeat-20°C |
CASNumber | 89430-38-6 |
PubChemID | 16143852 |
InChIKey | ZDXXOQXJCDHSRG-GGDSLUOHSA-N |
Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1588.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.63mL | 3.15mL | 6.29mL |
5mM | 0.13mL | 0.63mL | 1.26mL |
10mM | 0.06mL | 0.31mL | 0.63mL |
50mM | 0.01mL | 0.06mL | 0.13mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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