Overview:
TAR DNA binding protein (TARDBP) Human was originally discovered in a screen for transcriptional repressors of the transactive response (TAR) DNA binding element of the HIV-1 virus. Contain two RNA-recognition motifs (RRM1 and RRM2), one of which partially overlaps with a putative nuclear export sequence. Mutations in TARDBP were identified in amyotrophic lateral sclerosis (ALS) patients.
Gene Aliases:
ALS10; TARDBP
Genbank Number:
NM_007375
References:
1. Ou SH, et al: Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J Virol 69:3584–3596. 19952. Gitcho MA, et al. TDP-43 A315T mutation in familial motor neuron disease. Ann Neurol 2008 63:535–538. 2008
ebiomall.com
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IgM是免疫球蛋白M(Immunoglobulin M,IgM)的缩写。根据结构的不同将免疫球蛋白分为五种,IgM是人的免疫球蛋白之一,其他还有lgA、lgG、IgD和lgE。
HSV1型导致的一般都是腰部以上的感染,典型症状是水泡有可能引起脑炎,而且有非活化状态的潜伏。所以我觉得你根本就不用担心这个抗体IgG阳性的化验单。
2-IgM也是一种特异性感染指标,但在人体内持续时间不长(有时是30天更短),往往是传染病的近期感染指标。呈阴性是指:你近期没有感染过结核杆菌。
文章原文链接http://www.jbc.org/content/282/23/16776.long

