Tocris多肽 Tocris配体,Tocris/QS 11/3324/50/50 mg,球蛋白,天然蛋白,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/QS 11/3324/50/50 mg

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Tocris

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3324/50

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4000-520-616

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Description:ARFGAP1inhibitor;modulatesWnt/β-cateninsignaling

ChemicalName:(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GTPaseactivatingproteinofADP-ribosylationfactor1(ARFGAP1)inhibitor.ModulatesARF-GTPlevelsandsynergizeswiththeWnt/β-cateninsignalingpathwaytoupregulateβ-cateninnucleartranslocation.Alsoreducesinvitromigrationofmetastatichumanbreastcancercells.

TechnicalData

M.Wt	567.68
Formula	C₃₆H₃₃N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	944328-88-5
PubChemID	42623900
InChIKey	DOKZLKDGUQWMSX-HKBQPEDESA-N
Smiles	OC[C@H](CC6=CC=CC=C6)NC1=C2C(N(CC3=CC=C(C7=CC=CC=C7)C=C3)C=N2)=NC(OC4=CC=C(CCC5)C5=C4)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	56.77	100
	ethanol	56.77	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight567.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.76mL	8.81mL	17.62mL
5mM	0.35mL	1.76mL	3.52mL
10mM	0.18mL	0.88mL	1.76mL
50mM	0.04mL	0.18mL	0.35mL

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