BiologicalActivity
Guanylylcyclase(sGC)stimulator.IncreasesactivityofsGCbyupto92-foldatconcentrationsupto100μM.Inducesrelaxationofaorta,saphenousarteries,coronaryarteriesandveinsinvitro.Inhibitscollagen-inducedplateletaggregation.PromoteslipiduptakeintobrownADIposetissueandincreasesenergyexpenditureinmice.Inducesweightlossinobesemice.Antihypertensive.
TechnicalData
| M.Wt | 420.44 |
| Formula | C21H21FN8O |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 256498-66-5 |
| PubChemID | 9953906 |
| InChIKey | AQYFUZRYBJBAGZ-UHFFFAOYSA-N |
| Smiles | FC1=CC=CC=C1CN2N=C(C3=NC(N)=C(N4CCOCC4)C(N)=N3)C5=CC=CN=C52 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 4.2 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight420.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.38mL | 11.89mL | 23.78mL |
| 5mM | 0.48mL | 2.38mL | 4.76mL |
| 10mM | 0.24mL | 1.19mL | 2.38mL |
| 50mM | 0.05mL | 0.24mL | 0.48mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。