Overview:
Homosapienssuppressorofvariegation3-9homolog2(SUV39H2)isencodedbytheSUV39H2geneandbelongstothehistone-lysinemethyltransferasefamilyandSuvar3-9subfamily,ItcontainsanN-terminalchromodomainandaC-terminalSETdomain.Ittrimethylateslysine9ofhistoneH3,creatingabindingsiteforthechromodomainofHP1forepigenetictranscriptionalrepression.DeregulationofSUV39H2interfereswithmammalianhigher-orderchromatinorganization.
GeneAliases:
KMT1B;FLJ23414
GenbankNumber:
BC007754
References:
1.ReaS,etal:Regulationofchromatinstructurebysite-specifichistoneH3methyltransferases.Nature.10;406(6796):593-9,2000.2.AagaardL,etal:FunctionalmammalianhomologuesoftheDrosophilaPEV-modifierSu(var)3-9encodecentromere-associatedproteinswhichcomplexwiththehetero-chromatincomponentM31.EMBOJ.1;18(7):1923-38,1999.
ebiomall.com
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那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

