正品Tocris生物试剂1 Tocris小分子,Tocris/KH 7/3834/10/10 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/KH 7/3834/10/10 mg

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Tocris

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3834/10

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4000-520-616

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Description:Selectivesolubleadenylylcyclaseinhibitor

ChemicalName:(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivesolubleadenylylcyclase(sAC)inhibitor(IC₅₀=3-10μMinvivo).Inerttowardstransmembraneadenylylcyclase(tmAC)invitroandinwholecellsatconcentrationsupto300μM.BlockssynthesisofcAMPanddisplaysanantiapoptoticeffectatconcentrationsof1-100μM.

TechnicalData

M.Wt	419.3
Formula	C₁₇H₁₅BrN₄O₂S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	330676-02-3
PubChemID	6843191
InChIKey	GEHVZUUHMWNMAY-UHFFFAOYSA-N
Smiles	OC(C=CC(Br)=C2)=C2/C=N/NC(C(C)SC1=NC(C=CC=C3)=C3N1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.93	100
	ethanol	10.48	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.92mL	23.85mL
5mM	0.48mL	2.38mL	4.77mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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