BiologicalActivity
InhibitorofSir2p(IC50=60μM),anNAD+-dependentSir2familydeacetylaserequiredforchromatin-dependentsilencinginyeast.
CompoundLibraries
SplitomicinisalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 198.22 |
| Formula | C13H10O2 |
| Storage | Storeat-20°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 5690-03-9 |
| PubChemID | 5269 |
| InChIKey | ISFPDBUKMJDAJH-UHFFFAOYSA-N |
| Smiles | O=C1CCC2=C(O1)C=CC1=CC=CC=C21 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.82 | 100 | |
| ethanol | 19.82 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight198.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.04mL | 25.22mL | 50.45mL |
| 5mM | 1.01mL | 5.04mL | 10.09mL |
| 10mM | 0.5mL | 2.52mL | 5.04mL |
| 50mM | 0.1mL | 0.5mL | 1.01mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
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