Functionalizedvon-Hippel-Lindauproteinligand(VHL)forPROTACresearchanddevelopment;incorporatesanE3ligaseligandplusaPEGlinkerreadyforconjugationtoatargetproteinligand.PartofarangeoffunctionalizedtoolmoleculesforPROTACR&D.
Application
FunctionalizedVHLligandforPROTACs;incorporatesanE3ligaseligandplusaPEGlinker.
ProductInformation
Purity: >95%
MW: 656.23
Formula: C30H45N5O7S.HCl
CASNumber 2097971-11-2
PhysicalState: Lyophilizedwhitesolid
Quantity: 5mg;10mg;25mg
Solubility: 65mg/mLinDMSO;65mg/mLinwater
Storage: Storeat-20C.
References
1. Zengerle etal (2015)SelectivesmallmoleculeinduceddegradationoftheBETbromodomainproteinBRD4.ACSChem.Biol. 10 1770PMID: 26035625
2. Salami etal (2017)Wastedisposal-Anattractivestrategyforcancertherapy.Science 355 1163PMID: 28302825
Documents
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那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

