AMSH(AssociatedMoleculewiththeSH3-domainofSTAM)isaJAMMdomain-containingproteinthatregulatesreceptorendosomalsortingoftheepidermalgrowthfactorreceptor(EGFR)1.RecombinantAMSHfunctionsasadeubiquitylaseinvitroandablationofAMSHactivitybyincubationofcellswithAMSHsiRNAenhancesthedegradationofEGFR1.AMSHmediatedcleavageofK63linkedubiquitinchainsisenhancedinthepresenceofitsbindingpartnerSTAM2.
Info
| Amount | 250µg |
| State | Liquid |
| TargetMolecularWeight | 49kDa |
| Source | Chicken |
| Storage | Storeat-20°C |
| AlternativeNames | STAMBP,MGC126516,MGC126518,STAM-bindingprotein |
| Family | JAMM |
Applications
- RecommendedantibodydilutionsforWesternBlot:robustdetectionof100ngofrecombinantproteinat5µg/mL
Documents
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那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

