BasedonUBAdomainsknowntopossessahighaffinityforubiquitin,TandemUbiquitinBindingEntities(TUBEs)havebeendevelopedfortheisolationandidentificationofubiquitinatedproteins.TUBEsdisplayuptoa1000-foldincreaseinaffinityforpolyubiquitinmoietiesoverthesingleubiquitinbindingassociateddomain(UBA).Inaddition,TUBEshavebeendemonstratedtoprotectpolyubiquitinatedproteinsfrombothdeubiquitinationandproteasome-mediateddegradation,allowingforthedetectionofrelativelylowabundantproteinsthatcannotbedetectedwithcurrenttechnologies.
ThisproductisprotectedbyoneormoreUSorForeign patents.Pleasereadthe LimitedUseLabelLicense tolearnmore.Bypurchasingthisproduct,thepurchaseragreestocomply with theseterms.
Info
| AffinityTag | GST |
| MolecularWeight | 56kDa |
Applications
- Pulldownofpoly-ubiquitylatedproteinsfromcellandtissuelysates
- Protectionofpoly-ubiquitylatedproteinsfrombothdeubiquitylationanddegradationbytheproteasome
Benefits
- Upto1000-foldhigheraffinitythanthesingleUBAdomain
- Avoidoverexpressionofaffinity-taggedubiquitinsfor pulldowns
- Protectpoly-ubiquitinchainswithoutinhibitorsspecifictotheproteasomeordeubiquitylaseactivity
- Replace ubiquitinspecific antibodiesforenrichmentofpoly-ubiquitylatedproteins
Documents
ebiomall.com
>
>
>
>
>
>
>
>
>
>
>
>
那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

