This E2 is a SUMO-conjugating enzyme, also known as Ubc9. UBE2I can mediate the transfer of SUMO1, SUMO2, SUMO3 and SUMO4 from SUMO-activating enzyme E1 (UBLE1A-UBLE1B complex) to a substrate protein. This E2 enzyme has been shown to associate with the SUMO E3 ligases, RANBP2 or CBX4. This E2 conjugating enzyme is necessary for sumoylation and it is essential for nuclear architecture and chromosome segregation.
Info
| Amount | 0.8 nmol |
| State | Liquid |
| Molecular Weight | 19,000.9 Da |
| Source | Human Recombinant |
| Fusion Tag | His6 |
| Accession Number | P63279 |
| Alternate Names | Ubc9, Ubce9 |
| Storage | -80°C, avoid freeze/thaw cycles |
| Stability | 1 year under recommended storage conditions |
| Buffer | 20mM Tris, pH 7.5, 0.15M NaCl, 1mM EDTA |
Applications
- Identify cognate E2/E3 pairs
- Characterize upregulation/downregulation of E2 enzymes
- Build poly-ubiquitin chains
- Characterize ubiquitin chain specificity of E2 enzymes
- Analyze expression of E2 enzymes
Documents
ebiomall.com
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那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

