Anovelvirulencefactorwasidentifiedin Salmonellaenterica SEROvarTyphimurium. ThisfactorwasdeterminedtobeaproteinnamedSseL. SseListranslocatedfromthebacteriaintotheinfectedcellbyatypeIIIsecretionsystem. SseLhasde-ubiquitylatingactivityinvitroandaninfectionofcellswithaSseLmutantleadstoanaccumulationofubiquitylatedproteins. Thismutantstrainalsofailstocausemacrophagecelldeathwhichhasbeenimplicatedinthespreadandsystemicinfectionof Salmonella. Otherserovars,includingTyphi,ParatyphiAandCholeraesuiscontainsequencesencodingaproteinnearlyidenticaltoSseLsuggestingthatde-ubiquitylatingenzymesplayanimportantroleinthepathogenesisofother Salmonella serovars.
Info
Amount | 25µg |
State | Liquid |
MW | 37kDa |
Source | SalmonellaRecombinant |
FusionTag | His6 |
Storage | Storeat-80°C,avoidingrepeatedfreeze-thawcycles |
AlternativeNames | STM2287 |
ExpressionHost | E.coli |
SuggestedSubstrate | Ubiquitin-Rhodamine(Cat.# SI230) |
GeneID | |
Applications
- ThisenzymeisactiveintheUb-CHOPassay.
Documents
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那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

