Todate,fivehumancoronaviruses(CoV)havebeenidentifiedincludingthecommonhumanrespiratorypathogenNL63,thathasbeenshowntobeassociatedwithbothupperandlowerrespiratorytractdiseasesuchasbronchiolitisandcroup. TheprevalenceofNL63infectionsisillustratedbyepidemiologicalstudiesreportingthatNL63CoVwasdetectedin0.3-10%ofclinicalspecimensfrombothadultsandinfantsdiagnosedwithrespiratorytractdiseases.TheNL63genomeencodestwopapainlikeproteases,PLP1andPLP2.PLP2isadualspecificityisopeptidasewithbothdeubiquitylaseanddeISGylaseactivity.PLP2cleavesUb-PLA2 andISG15-PLA2 withhighandmoderateefficiencyrespectively.
Info
Amount | 25µg |
State | Liquid |
MW | 36.7kDa |
Source | NL63-CoVRecombinant |
FusionTag | His6 |
Storage | Storeat-80°C,avoidingrepeatedfreeze-thawcycles. |
ExpressionHost | E.coli |
SuggestedSubstrate | Ubiquitin-Rhodamine(Cat.# SI230)&ISG15-AMC |
GeneID |
Applications
- ThisenzymeisactiveintheUb-Rhodamine,Ub-CHOPandISG15-CHOPassay.
Documents
ebiomall.com
>
>
>
>
>
>
>
>
>
>
>
>
那糖酵解中依赖NAD的酶不是要在线粒体内反应?
蛋白酶分布广泛,主要存在于人和动物消化道中,而消化道通过口与肛门与外界相通,属于外环境或外界环境
(溶菌酶、凝血酶原等)分布在内环境
(消化)酶分布在消化道

