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Description:Highaffinityangiotensin-convertingenzyme(ACE)ligand
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Highaffinityangiotensin-convertingenzyme(ACE)ligand(Kd=2.79nM).ExhibitsnosignificanteffectonACEenzymaticactivityupto500nMconcentration.PotentiatesNMDA+D-serine-induceddopaminereleasefromstriatalslicesinvitroandthestriatuminvivo.
TechnicalData
| M.Wt | 932.5 |
| Formula | C43H68N10O13 |
| Sequence | PPTTTKFAA |
| Storage | Storeat-20°C |
| PubChemID | 122177132 |
| InChIKey | VFPBWEDFCUSZRJ-BRCVGTSGSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto2mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight932.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.07mL | 5.36mL | 10.72mL |
| 5mM | 0.21mL | 1.07mL | 2.14mL |
| 10mM | 0.11mL | 0.54mL | 1.07mL |
| 50mM | 0.02mL | 0.11mL | 0.21mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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