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Description:Highaffinityasparticproteaseinhibitor;inhibitsHIV-1/2proteinases
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Highaffinityasparticproteaseinhibitor.InhibitsHIV-1protease(Ki=20nMatpH4.7)andHIV-2protease(Ki=5nMatpH4.7).Antiviral.
TechnicalData
| M.Wt | 643.81 |
| Formula | C31H57N5O9 |
| Sequence | VVA (Modifications:Val-1=N-terminalAc,Val-2=Val-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl,Ala-3=Ala-(3S,4S)4-amino-3-hydroxy-6-methylheptanoic-acid) |
| Storage | Storeat-20°C |
| CASNumber | 11076-29-2 |
| PubChemID | 5481345 |
| InChIKey | WKYBEGDEGRCZNF-LBTYKNIQSA-N |
| Smiles | O=C(N[C@@H](CC(C)C)[C@@H](O)CC(N[C@@H](C)C(N[C@H]([C@@H](O)CC(O)=O)CC(C)C)=O)=O)[C@H]([C@@H](C)C)NC([C@@H](NC(C)=O)C(C)C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto2mg/mlinPBS |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight643.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.55mL | 7.77mL | 15.53mL |
| 5mM | 0.31mL | 1.55mL | 3.11mL |
| 10mM | 0.16mL | 0.78mL | 1.55mL |
| 50mM | 0.03mL | 0.16mL | 0.31mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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