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Description:Cathepsininhibitor
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
VerypotentinhibitorofcathepsinL(Ki=0.6nM)andthestrongestinhibitorofcathepsinB(Ki=100nM)amongstthepeptidealdehydes.AlsoinhibitsprocessingofmalariaaspartichemoglobinasesplasmepsinsIandIIinvitro.
TechnicalData
| M.Wt | 401.56 |
| Formula | C19H35N3O4S |
| Storage | Storeat-20°C |
| CASNumber | 136632-32-1 |
| PubChemID | 4331 |
| InChIKey | RJWLAIMXRBDUMH-UHFFFAOYSA-N |
| Smiles | O=C(C)NC(C(NC(C(NC(C([H])=O)CCSC)=O)CC(C)C)=O)CC(C)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.16 | 100 | |
| ethanol | 4.02 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight401.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.49mL | 12.45mL | 24.9mL |
| 5mM | 0.5mL | 2.49mL | 4.98mL |
| 10mM | 0.25mL | 1.25mL | 2.49mL |
| 50mM | 0.05mL | 0.25mL | 0.5mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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