Tocris抗体，试剂，血清，细胞 Tocris抗体,Tocris/CA 074/4863/1/1 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/CA 074/4863/1/1 mg

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Tocris

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4863/1

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4000-520-616

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Description:SelectivecathepsinBinhibitor

ChemicalName:N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofcathepsinB(K_i=2-5nM).DisplaysselectivityovercathepsinsHandL(K_i=40-200μM).Showntoreducebonemetastasisina4T1.2breastcancermodel.

TechnicalData

M.Wt	383.44
Formula	C₁₈H₂₉N₃O₆
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	134448-10-5
PubChemID	9821383
InChIKey	ZEZGJKSEBRELAS-PEDHHIEDSA-N
Smiles	O=[C@](NCCC)[C@H]1O[C@@H]1[C@@](N[C@@H]([C@@H](C)CC)[C@](N2[C@H](C(O)=O)CCC2)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	7.67	20
	ethanol	7.67	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight383.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.61mL	13.04mL	26.08mL
5mM	0.52mL	2.61mL	5.22mL
10mM	0.26mL	1.3mL	2.61mL
50mM	0.05mL	0.26mL	0.52mL

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BiologicalActivity

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PreparingStockSolutions

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