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Description:SelectiveinhibitorofMMP-13
ChemicalName:N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
SelectiveinhibitorofMMP-13(89%inhibitionat10μg/mL)thatdisplaysnoactivityatMMP-1,MMP-9orTACE.InhibitsinvitroinvasionbythehumanpituitaryadenomacelllineHP75.
TechnicalData
| M.Wt | 338.83 |
| Formula | C17H23N2O3.HCl |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 1188890-36-9 |
| PubChemID | 16760373 |
| InChIKey | PIOACXKZWXHBRB-UHFFFAOYSA-N |
| Smiles | Cl.O=C(NCCCCN1CCOCC1)C1=CC2=CC=CC=C2O1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.41 | 75 | |
| water | 33.88 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight338.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.95mL | 14.76mL | 29.51mL |
| 5mM | 0.59mL | 2.95mL | 5.9mL |
| 10mM | 0.3mL | 1.48mL | 2.95mL |
| 50mM | 0.06mL | 0.3mL | 0.59mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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