Tocris产品促销 Tocris信号通路抑制剂,Tocris/Calcineurin Autoinhibitory Peptide/1891/1/1 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Calcineurin Autoinhibitory Peptide/1891/1/1 mg

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Tocris/Calcineurin Autoinhibitory Peptide/1891/1/1 mg

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Tocris

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1891/1

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Description:Selectivecalcineurininhibitor

AlternativeNames:Autoinhibitorypeptide457-482

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofCa²⁺-calmodulin-dependentproteinphosphatase(calcineurin)(IC₅₀~10μM).DoesnotinhibitPP1,PP2AorCaMkinaseII(IC₅₀>100mM).

TechnicalData

M.Wt	2930.34
Formula	C₁₂₄H₂₀₅N₃₉O₃₉S₂
Sequence	ITSFEEAKGLDRINERMPPRRDAMP
Storage	Desiccateat-20°C
CASNumber	148067-21-4
PubChemID	90488720
InChIKey	JRQDGUSHUYLSHC-TVQDNDAUSA-N
Smiles	[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto1mg/mlinwater

Solubility

Solubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2930.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.34mL	1.71mL	3.41mL
5mM	0.07mL	0.34mL	0.68mL
10mM	0.03mL	0.17mL	0.34mL
50mM	0.01mL	0.03mL	0.07mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

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